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Using Wellbutrin for Weight Gain

Wellbutrin is an antidepressant built with weight gain in mind. It is made to affect neither weight gain or loss, effectively maintaining weight while working to fight depression and anxiety. As far as antidepressants go, this is the best for weight gain. Although this is true, there are cases where body weight can be affected by Wellbutrin.

We’ll look at what Wellbutrin is, how it can affect weight gain, and how it could potentially cause weight gain in some circumstances.

That being said, we agree that this is the best antidepressant for people with weight gain concerns.

Wellbutrin and Weight Gain


Wellbutrin is a brand name product for the generic drug bupropion. It is an antidepressant medication that is designed for treating major depressive disorder and seasonal affective disorder.

This medication is also often used as an aid to quit smoking and is most commonly taken in as a tablet.

It is supposed to differentiate from other antidepressants in that it does not have a large effect on weight gain or sexual dysfunction. However, it can – and has been known – to affect weight gain in some cases.

In theory, you should be able to take Wellbutrin without experiencing weight gain, as it is not meant to have an affect on metabolism or weight.

What Does Wellbutrin Do?

Approved in 1989 to be used medically, Wellbutrin is an atypical antidepressant and smoking cessation aid because unlike other products. It essentially functions as a norepinephrine-dopamine reuptake inhibitor (NDRI), inhibiting reuptake of certain neurotransmitters that cause stimulation.

Taking Wellbutrin should result in a boost in energy, focus, and help combat feelings of depression.

The Side Effects of Wellbutrin


Side EffectsUnlike the more commonly used serotonergic (SSRI) antidepressant, these carry with them fewer side effects. Sexual dysfunction and weight gain are actually the two main things that are not supposed to be affected by Wellbutrin that other antidepressants are likely to affect.

Therefore, Wellbutrin is actually one of the few antidepressants that shouldn’t lead to weight gain or loss. Ideally and theoretically, Wellbutrin is actually the best antidepressant for weight loss.

However, medications affect people differently, and although it is uncommon and unlikely, that does not mean it can’t occur. If anything, Wellbutrin is more likely to cause weight loss than weight gain as well, so it is relatively unlikely that weight gain is actually caused by Wellbutrin in many cases.

The Ways Wellbutrin Can Cause Weight Gain

All of the suggested reasons for Wellbutrin’s effects on weight gain relate to the idea of changes in appetite. One of the main reasons you may experience weight gain on Wellbutrin would be because it can affect your appetite.

Although it is more commonly associated with causing weight loss than weight gain, it is possible to gain weight while on Wellbutrin. It can potentially increase your cravings for certain foods, such as sweets and carbohydrate rich products. This can help lead to weight gain or loss depending on how Wellbutrin is affecting your appetite.

Wellbutrin Weight Gain


A big factor as to why Wellbutrin is the suggested and best antidepressant for weight gain is because it is designed to be weight neutral, causing neither weight gain nor loss. In general, Wellbutrin is safe to take and is the best option when concerned about weight gain.

Hormonal changes can also potentially impact appetite and metabolism. Since Wellbutrin can affect stress hormones known as cortisol, these levels can affect metabolism in the boy. Therefore, hormonal changes caused by Wellbutrin will again impact the appetite of the person.

Choosing Wellbutrin for Weight Gain

When it comes down to it, Wellbutrin is one of the best antidepressants for weight gain. It is designed to be weight neutral, causing patients to neither gain nor lose weight. Ideally, this product is best suited for people who have weight gain as a major concern.

Wellbutrin weight gain is different from more common types of antidepressants in that it operates as an NDRI, which does not directly affect metabolism or appetite and therefore should have the least impact on weight.

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